In a groundbreaking breakthrough, scientists have successfully created transgenic mice with luxurious golden fur inspired by the woolly mammoth. But can this achievement be scaled up to bring back extinct species like the elephant? The journey to de-extinction is fraught with challenges and uncertainties.
The Challenges Ahead of De-Extinction
Success with mice does not guarantee success with elephants. The creation of transgenic mice with long, luxurious golden locks of tufted fur inspired by the coats of woolly mammoths has been hailed as a significant breakthrough in the field of de-extinction.
However, critics argue that this achievement is only the beginning and that many hurdles still need to be overcome before bringing back extinct species like the woolly mammoth. One of the main concerns is that the process of de-extinction may not be able to fully replicate the characteristics of the original species.
Understanding the Complexity of De-Extinction
De-extinction involves using genetic engineering to introduce desired traits into an organism. In the case of the woolly mouse, scientists have successfully created mice with a combination of genes that give them long, thick fur similar to that of the woolly mammoth.
However, this achievement raises questions about whether it is possible to fully replicate the characteristics of the original species. The creation of transgenic elephants is also underway, but the process is much more complex and time-consuming than creating mice.
The Role of Genetics in De-Extinction
Genetics plays a crucial role in de-extinction efforts. By analyzing the genetic instructions of extinct species, scientists can identify genes that may have contributed to their characteristics. In the case of the woolly mouse, scientists analyzed the genomes of 121 mammoth and elephant samples to identify genes that may have given woolly mammoths their characteristic traits.

Genetics is the study of heredity, genes, and variation.
It examines how traits are passed down from parents to offspring through DNA.
The human genome consists of approximately 20,000-25,000 protein-coding genes.
Genetic variation occurs due to mutations, genetic recombination during reproduction, or gene flow from one population to another.
Understanding genetics is essential for fields like medicine, agriculture, and forensic science.
The Challenges of Cloning Extinct Species
Cloning extinct species is a complex task that requires significant resources and expertise. The process involves taking cells from an extinct species and using genetic engineering to introduce desired traits into the organism.
However, cloning extinct species is not as simple as it sounds. One major challenge is that the cells used for cloning are often degraded over time, making it difficult to obtain viable cells.
The Future of De-Extinction
Despite the challenges ahead, many scientists remain optimistic about the future of de-extinction efforts. The creation of transgenic mice and elephants has shown that it is possible to introduce desired traits into an organism using genetic engineering.
However, more research is needed to fully understand the complexities of de-extinction and to overcome the hurdles that need to be addressed.
De-extinction, the process of reviving extinct species, poses significant scientific and ethical challenges.
One major hurdle is the lack of suitable DNA samples from extinct individuals.
Even with advanced technology, DNA degradation over time makes it difficult to recover intact genetic material.
Furthermore, reintroducing a de-extinct species into a modern ecosystem can disrupt native populations and ecosystems.
Additionally, de-extinction raises questions about the ethics of playing God and altering natural processes.
- sciencenews.org | ‘Woolly mice’ were just a start. De extinction still faces many hurdles