Eli Lilly’s GLP-1 pill, orforglipron, has shown promising benefits in improving blood sugar levels and aiding weight loss, with participants losing an average of 16 pounds over 40 weeks. Novo Nordisk’s stock price tumbles as the company faces unprecedented challenges.
Shares of Novo Nordisk, the Danish pharmaceutical company behind GLP-1 weight loss drugs ‘Semaglutide“>Ozempic[/highlight]‘ and ‘Wegovy‘, have plummeted over eight percent on Thursday. The company’s stock value has been sliding for months, with a 34 percent decline so far this year, following major supply line disruptions that have pushed physicians to prescribe alternative injectable drugs.
Novo Nordisk is a Danish multinational pharmaceutical company headquartered in Bagsværd, 'Denmark' .
Founded in 1923 as a sugar factory, the company began producing insulin in 1925 and has since become a leading manufacturer of diabetes medications.
Today, Novo Nordisk develops and markets innovative treatments for chronic diseases such as obesity, growth hormone disorders, and rare blood clotting disorders.
The company operates globally with a presence in over 140 countries.
The latest development is the announcement of Eli Lilly‘s Phase 3 trial results for its GLP-1 pill ‘orforglipron‘, marketed under the brand name ‘CagriSema‘. The once-a-day pill has shown promising benefits in improving blood sugar levels and aiding weight loss, with participants losing an average of 16 pounds over 40 weeks.
Eli Lilly and Company is a multinational pharmaceutical corporation headquartered in Indianapolis, Indiana.
Founded in 1876 by Colonel Eli Lilly, the company has grown to become one of the world's largest pharmaceutical companies.
Eli Lilly develops and manufactures innovative medicines in areas such as oncology, diabetes, and immunology.
The company operates in over 18 countries and employs approximately 36,000 people globally.
Novo Nordisk‘s injectable peptide, ‘semaglutide’, is also difficult to manufacture, suggesting Eli Lilly may have a competitive edge. With no comparable small-molecule drug to Eli Lilly‘s ‘orforglipron’, Novo Nordisk‘s options are limited. The company’s stock price has been hammered, and investors have taken notice, embracing Eli Lilly as the leader in the obesity drug market.
A Shift in Market Power

The emergence of a next-generation obesity drug is evident with Eli Lilly‘s promising results. However, it’s still too early to draw definitive conclusions or declare winners just yet. Novo Nordisk plans to submit data from its latest trials to the FDA by the end of the year for weight loss management and for treating type 2 diabetes in early 2026.
The market is witnessing a series of radical shakeups, and it’s unclear whether investors’ current call on Eli Lilly will be the right one in the long term. As the landscape continues to evolve, pharmaceutical companies must adapt to stay competitive. With major supply line disruptions already affecting Novo Nordisk‘s stock value, the company’s ability to respond to this shift is crucial.
A New Era for Obesity Drugs?
The development of a weight loss pill by Pfizer was scrapped earlier in the week after a participant reported a liver injury during a clinical trial. This setback highlights the risks associated with obesity drug development and the need for rigorous testing and regulatory oversight.
Eli Lilly‘s ‘promising’ results could hint at the pill being a viable alternative to Novo Nordisk‘s ‘Semaglutide“>Ozempic[/highlight]‘ and even the company’s own drugs ‘Zepbound‘ and ‘Mounjaro‘. However, it’s essential to approach this new development with caution and wait for further data before making any conclusions.
The obesity drug market is highly competitive, and pharmaceutical companies must navigate complex regulatory environments to bring innovative treatments to patients. As the landscape continues to shift, investors and stakeholders must remain vigilant and adapt to changing market dynamics.
- futurism.com | Novo Nordisk Is Getting Absolutely Destroyed